Mind + Muscle

technical minds + legal muscle

Bracket
Sterne Kessler Goldstein Fox
David W. Roadcap, Ph.D.

Mind + Muscle

David W. Roadcap, Ph.D.

Associate

 
  • David W. Roadcap, Ph.D.
  • p 202.772.8757
  • f 202.371.2540
  • droadcap@skgf.com

  • v-card

Dr. Roadcap is an associate in the Biotechnology/Chemical group.  He has extensive experience both in the preparation and prosecution of patents and in litigation matters.  Dr. Roadcap’s litigation experience includes involvement in all phases of inter partes review proceedings before the Patent Trial and Appeal Board at the USPTO, as well as in proceedings before the United States International Trade Commission.  Dr. Roadcap’s primary technical areas of expertise are in the areas of pharmacology, cancer biology, cell biology, biochemistry, microscopy, and molecular biology.

Prior to his legal endeavors, Dr. Roadcap was a post-doctoral researcher at the Lineberger Comprehensive Cancer Center at the University of North Carolina.  There, he performed translational research on cancer cells with the goal of elucidating the molecular basis for the motility of metastatic melanoma cells.  Dr. Roadcap’s graduate work was performed at Duke University, where he received his PhD in the department of Pharmacology and Cancer Biology.  His work there was dedicated to understanding the role of protein phosphatases in regulating cytoskeletal dynamics in dendritic spines, particularly during development and as part of learning and memory.  As a result of his research endeavors, Dr. Roadcap is an author on seven research publications in high impact peer-reviewed journals.  Further, he is an author on three literature reviews, has presented his work at seven national and international meetings, and has been selected as a speaker at an international cancer research conference.  He has been supported by a Ruth Kirschstein NRSA Post-Doctoral Fellowship as well as a Lineberger Cancer Center Postdoctoral Fellowship.

Legal Publications
  • Roadcap DW, An International Examination of ITC‐Like Alternate Jurisdictions for Patent
    Litigation
    , 337 Reporter, Vol. XXXVI (Summer, 2012).
  • Roadcap, DW. Global‐Tech Appliances, Inc. v. SEB S.A. and the Creation of a Flexible
    Blindness Standard for Induced Patent Infringement
    . 13 N.C. J.L. & Tech. On. 117
    (December, 2011).
Scientific Publications
  • Liu W, Monahan KB, Pfefferle AD, Shimamura T, Sorrentino J, Chan KT, Roadcap DW,
    Ollila DW, Thomas NE, Castrillon DH, Miller CR, Perou CM, Wong KK, Bear JE, Sharpless
    NE, LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation
    in melanoma, Cancer Cell 21(6):751‐64 (June, 2012).
  • Chan KT, Roadcap DW, Holoweckyj N, Bear JE. Coronin 1C harbours a second actinbinding
    site that confers co‐operative binding to F‐actin
    . Biochem J. 444(1):89‐96 (May,
    2012).
  • Roadcap DW, Bear JE. Double JMY: making actin fast. Nat Cell Biol. 11(4):375‐6 (April,
    2009).
  • Roadcap DW, Clemen CS, Bear JE. The role of mammalian coronins in development and
    disease
    . Subcell Biochem. 48:124‐35 (2008).
  • Shiow LR, Roadcap DW, Paris K, Watson SR, Grigorova IL, Lebet T, An J, Xu Y, Jenne CN,
    Föger N, Sorensen RU, Goodnow CC, Bear JE, Puck JM, Cyster JG. The actin regulator
    coronin 1A is mutant in a thymic egress‐deficient mouse strain and in a patient with
    severe combined immunodeficiency
    . Nat Immunol. 9(11):1307‐15 (Nov., 2008).
  • Roadcap DW, Brush MH, Shenolikar S. Identification of cellular protein phosphatase‐1
    regulators
    . Methods Mol Biol. 365:181‐96 (2007).
    Hu XD, Huang Q, Roadcap DW, Shenolikar SS, Xia H. Actin‐associated neurabin‐protein
    phosphatase‐1 complex regulates hippocampal plasticity. J Neurochem. 98(6):1841‐51
    (Sep., 2006).
  • Terry‐Lorenzo RT*, Roadcap DW*, Otsuka T, Blanpied TA, Zamorano PL, Garner CC,
    Shenolikar S, Ehlers MD. Neurabin/protein phosphatase‐1 complex regulates dendritic
    spine morphogenesis and maturation
    . Mol Biol Cell. 16(5):2349‐62 (May, 2005).
  • Webb DJ, Roadcap DW, Dhakephalkar A, Gonias SL. A 16‐amino acid peptide from
    human alpha2‐macroglobulin binds transforming growth factor‐beta and plateletderived
    growth factor‐BB
    . Protein Sci. 9(10):1986‐92 (Oct., 2000).
  • Gonias SL, Carmichael A, Mettenburg JM, Roadcap DW, Irvin WP, Webb DJ. Identical or
    overlapping sequences in the primary structure of human alpha(2)‐macroglobulin are
    responsible for the binding of nerve growth factor‐beta, platelet‐derived growth factor‐BB, and transforming growth factor‐beta.
    J Biol Chem. 275(8):5826‐31 (Feb., 2000).
  • Admissions
      • District of Columbia

      • North Carolina

      • United States Patent and Trademark Office

  • Education
    • J.D., University of North Carolina - Chapel Hill

    • Ph.D., Pharmacology and Cancer Biology, Duke University

    • B.A., Biochemistry/Biology, University of Virginia with highest honors

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